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AstraZeneca's potential blockbuster ADC was recognized by the FDA. AstraZeneca and Thirteen announced that the FDA granted its Trop2 targeted antibody-coupled drug (ADC) Datopotamab Deruxtecan (Dato-DXD) breakthrough therapy recognition (BTD) to treat adult patients with locally advanced or metastatic epidermal growth factor receptor mutation (EGFRm) who are undergoing treatment.The Turkish Foreign Ministry strongly condemns Israel's entry into Syrian territory.Hangzhou Gaoxin: Liaoning Zhongke plans to reduce its shareholding by no more than 1%. Hangzhou Gaoxin announced that Liaoning Zhongke, a shareholder holding 5.68%, plans to reduce its shareholding by no more than 1,266,700 shares through centralized bidding or block trading within 3 months after 15 trading days from the date of announcement, accounting for 1% of the company's total share capital. The reason for the reduction is the shareholders' own capital turnover demand. Liaoning Zhongke currently holds 7.1933 million shares of the company, accounting for 5.68% of the total share capital. The reduction plan will be implemented according to the market situation and stock price, and will not affect the company's control and going concern. The company will urge it to implement the reduction plan legally and in compliance and fulfill its information disclosure obligations.

Belarusian President Lukashenko: Belarus has dozens of nuclear warheads.Gaza Civil Defence Department: Israeli attack on northern Gaza killed 25 people.GD Helicopter Finance signed a financing agreement of over 77 million euros. According to G&D Airlines, GD Helicopter Finance signed a financing agreement of over 77 million euros with Bank of China, London Branch and German Helaba Bank to support GDHF in purchasing several new Airbus H160 helicopters.

Boeing also exposed nearly 1,000 layoffs. According to American media reports, American aircraft manufacturer Boeing will lay off employees again, involving nearly 1,000 people in Washington State and California. This batch of layoffs is part of Boeing's plan to lay off 17,000 people worldwide announced in October. The Associated Press reported on the 9th that Boeing's latest layoffs involved nearly 400 people in Washington State and more than 500 people in California. The posts to be abolished include engineers, personnel and analysts, affecting Boeing's civil, defense and global service departments. In a document submitted to the government in mid-November, Boeing said that it plans to lay off about 2,500 people, and with the latest report of nearly 1,000 people, Boeing has recently laid off about 3,500 people. Kelly Otterberg, CEO of Boeing, said that layoffs are not due to strikes, but to redundancy. The strike of Boeing's 33,000 people's congress lasted for nearly two months, which caused the production of Boeing's various passenger planes to encounter obstacles. The workers who took part in the strike voted on November 4 to accept the terms of the new labor agreement and end the strike. According to an insider's disclosure on the 9th, Boeing resumed production of the 737 MAX passenger plane on the 6th. Reuters commented that it is very important for Boeing to restart the production of this aircraft. Boeing now holds about 4,200 orders for 737 MAX. (Xinhua News Agency)In the first 11 months of this year, the national railway construction made a new breakthrough. Since this year, the construction of railway projects in many places in China has made a new breakthrough. The reporter learned from China National Railway Group Co., Ltd. that from January to November this year, the national railway completed fixed assets investment of 711.7 billion yuan, up 11.1% year-on-year, and the construction of modern railway infrastructure system was promoted with high quality, which gave full play to the effective driving role of railway investment in the whole society. Recently, a number of railway projects have been opened or will be opened soon: the Milan-Ruoqiang section of Lop Nur-Ruoqiang Railway has been opened for operation; Shanghai started trial operation via Suzhou-Huzhou high-speed railway, Jining via Datong-Yuanping high-speed railway, and Huairou-Daxing intercity railway from Langfang North to Daxing Airport. At the same time, the railway department promoted railway construction with high quality and efficiency, strengthened safety, quality, environmental protection and investment control, and made positive progress in a number of key projects. (Xinhua News Agency)UBS raised its target price for Oracle Bone Inscriptions from $200 to $210.